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08.04.2022


Painfully worn knee? Supplementation with ASU may reduce your problem

If you suffer from joint problems, as a reader of this free web magazine you will think of supplementation with glucosamine, whether or not in combination with chondroitin. If you do not or do not respond well to this, there is an alternative.
Ever heard of ASU?


Painfully worn knee? Supplementation with ASU may reduce your problem


ASU
ASU stands for avocado and soybean unsaponifiables. It is an extract of avocado and soy that was developed in the late 1980s by the French Expanscience Laboratoires.

Expanscience markets ASU as Piascledine. It contains carotenoids such as lutein, phytosterols, various forms of vitamin E and chlorophyll.

Expanscience discovered that in test tubes ASU allows cartilage cells to produce a little more collagen and, above all, inhibits the activity of catabolic inflammatory proteins. As a result, ASU can alleviate chronic ailments in which joints deteriorate.


Painfully worn knee? Supplementation with ASU may reduce your problem


Study
Piotr Gluszko and Malgorzata Stasiek, two rheumatologists from the Polish National Institute of Geriatrics, wanted to find out whether the application of ASU could be useful in practice. They collected data from 99 medical centers in Poland, where a total of 4,822 people with a worn knee were willing to take a capsule containing 300 milligrams of ASU daily for six months.

Of that group, 4186 subjects completed the experiment. That is a lot.

Gluszko and Stasiek did not use a placebo group. The subjects knew what ASU was and should do.

Results
During the trial, the amount of pain that the subjects reported at rest decreased. Unsurprisingly, the use of painkillers declined.


Painfully worn knee? Supplementation with ASU may reduce your problem


Painfully worn knee? Supplementation with ASU may reduce your problem


During the trial, the pain experienced by the subjects while walking decreased by two-thirds.

The researchers used the Lequesne questionnaire to determine how much trouble the subjects had in daily life from their worn knee joints. The higher you score on that questionnaire, the bigger your problems.

During the trial, the mean scores decreased by half.


Painfully worn knee? Supplementation with ASU may reduce your problem


Painfully worn knee? Supplementation with ASU may reduce your problem


Click on the table above for a larger version.

There were no serious side effects, according to the researchers.

Conclusion
"The results of our survey support recommendations indicating the usefulness of ASU in a routine symptomatic treatment of knee osteoarthritis", resume Gluszko and Stasiek.

Sponsor
The research was funded by Angelini Poland. [angelinipharma.pl] Angelini is an internationally operating medical research company. We have not been able to determine whether Angelini has a business interest in Expanscience Laboratoires.

Source:
Reumatologia. 2016;54(5):217-26.

More:
How avocatin-B, the FAO inhibitor in avocado, protects against type 2 diabetes 15.12.2019
Avocados improve your cardiovascular health even more than you think 25.11.2019

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