Improved response to carbohydrates by beta-glucans from oats
If diabetics ingest about 3.5 grams of oat-derived beta-glucans every day, their glucose metabolism improves. Consuming 70 grams of oatmeal daily has the same effect.
Researchers from the University of Toronto in Canada collected 8 trials involving a total of 407 adults with type 2 diabetes. All test subjects were treated for their condition, but some of them also received beta-glucans from oatmeal.
The researchers used trials in which subjects were given oat-derived beta-glucans, oat fiber or regular oatmeal. The latter two foods consist of 6.9 and 5 percent beta-glucans, respectively.
The daily dose of beta-glucans that the subjects received ranged from 2 to 5.3 grams of beta-glucans per day. The average dose was about 3.5 grams of beta-glucans per day, the average trials took about 4 weeks.
The Canadians aggregated the data from the trials and re-analyzed it.
The concentration of HbA1C (a marker for exposure to glucose over a longer period) and the glucose level early in the morning before breakfast were reduced by supplementation. The effects were not large, but large enough to have a positive health effect.
The HOMA-IR, a measure of insulin resistance, also improved. However, this effect was trivial.
Click on the figure below for a larger version.
The most important effect was the decrease in the fasting glucose level. The statistical significance was relatively strong.
"Oats and oat beta-glucan consumption over the short-term to moderate-term results in improvements in established markers of fasting and postprandial glycemic control beyond concurrent therapy in adults with type 2 diabetes who were predominantly middle-aged, overweight or obese and with moderately controlled diabetes treated by antihyperglycemic medications or insulin", the Canadians write.
BMJ Open Diab ResCare 2022;10:e002784.
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Insulin & Glucose Metabolism