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20.06.2024

Vitamin D works even better against eczema in combination with vitamin E

Vitamin D supplementation reduces eczema by about thirty percent, we reported a few days ago. In combination with supplementation with vitamin E, this protective effect may become considerably stronger.

Study
In 2011, a small trial was published in the Journal of Dermatological Treatment, in which 45 people with eczema participated as test subjects.

The researchers, nutritional biochemists affiliated with Tehran University of Medical Sciences, divided the test subjects into 4 groups. There was a placebo group, a vitamin D group, a vitamin E group and a group that received both vitamin D and vitamin D.

The trial lasted 60 days.

The subjects who received vitamin D took 40 micrograms of vitamin D3 daily. The subjects who received vitamin E took a cheap supplement containing 265 milligrams of synthetic alpha-tocopherol every day.

Results
The researchers determined the severity of the eczema using a SCORAD score. During the trial, that score dropped by 35-36 percent in the vitamin D group and the vitamin E group. The decrease in the placebo group was of a similar order.

However, the combination of both vitamins reduced the SCORAD score by 64 percent. That was significantly more than the decrease in the placebo group.

Click on the table for a larger version.

Mechanism
Vitamin E is found in nuts and seeds. The vitamin plays a role in keeping the skin healthy. [Indian Dermatol Online J. 2016 Jul-Aug;7(4):311-5.]

Adults need about 15-20 milligrams of vitamin E every day, but large groups do not achieve this. The average daily intake is probably closer to 6 milligrams. [Int J Vitam Nutr Res. 2015 Dec;85(5-6):261-81.] In the trial we discussed above, supplementation may have compensated for a deficient intake of vitamin E.

Conclusion
The number of subjects in this trial was small, according to the researchers themselves. "Studies with a larger sample size are needed to draw a conclusion," they write.

Source:
J Dermatolog Treat. 2011 Jun;22(3):144-50.

More:
With or without hydrocortisone, supplementing with vitamin D reduces eczema 06.06.2023

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