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06.09.2023


Painful knee joint? Calcium fructoborate helps within a few days

If you suffer from a painful knee that also no longer functions properly, supplementing with calcium fructoborate may partially solve your problem. According to a study published in Clinical Interventions in Aging, calcium fructoborate takes effect after just a few days.


Painful knee joint? Calcium fructoborate helps within a few days


Study
In 2014, researchers at FutureCeuticals, a producer of active substances for supplements and functional foods, published a trial involving 60 subjects aged 35-65 with a painful knee joint. Half of them received a placebo every day for 14 days. During the same period, the other half took 2 capsules daily, each containing 110 milligrams of calcium fructoborate.

Calcium fructorate is a form of boron, which has recently been authorized in the EU. [EFSA Journal 2021;19(7):6661.] The maximum dose is 220 milligrams of calcium fructoborate per day.

FutereCeuticals markets calcium fructoborate as FruiteX-B. Therefore, we classify the study as 'sponsored'.


Painful knee joint? Calcium fructoborate helps within a few days


Results
According to the study participants, supplementation with calcium fructoborate improved knee function [WOMAC score] and reduced pain [MPQ score].

The lower the WOMAC and MPQ scores, the better. The WOMAC score ranges from 0-96, the MPQ score from 0-78.


Painful knee joint? Calcium fructoborate helps within a few days


Mechanism
In other studies, calcium fructoborate lowers the concentration of the inflammatory protein CRP in the blood. Inhibition of inflammation could theoretically explain the reported effects. However, the researchers in the trial we are talking about could find no effect on CRP.

Conclusion
"This comparative double-blind study has confirmed the effect of calcium fructoborate, showing significant improvements in knee discomfort and function over a period of 2 weeks", summarize the researchers. "However, the inflammatory markers that are targeted and the mechanism of action are still unknown."

"A future clinical study would help clarify the above, as well as the effect of the calcium fructoborate supplementation on a long-term basis."

Source:
Clin Interv Aging. 2014 Jun 5;9:895-9.

More:
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Is boron a life extender? 15.02.2023
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Breakfast boron capsule boosts testosterone 29.07.2011

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