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02.03.2022


Over 65? A high Q10 level gives you a healthy heart and well-functioning muscles

A high Q10 level helps people over 65 prevent heart attacks, and at the same time ensures that their muscles continue to function adequately. That's what a Spanish epidemiological study recently published in Antioxidants suggests.


Over 65? A high Q10 level gives you a healthy heart and well-functioning muscles


Study
Spanish physiologists, affiliated with Universidad Pablo de Olavide, recruited 64 healthy people over 65 in a care home and two activity centers for senior citizens. They analyzed the blood composition of the study participants, and measured their physical functioning with standard exercise tests.

Results
Based on their cholesterol composition, the Spaniards divided the study participants into a group with an increased risk of cardiovascular disease and a group with no cardiovascular risk. When they subsequently measured the Q10 levels of both groups, they found a positive association between a relatively high Q10 level and the absence of a cardiovascular risk.

The association was especially strong among women.

Click on the figure below for a larger version.


Over 65? A high Q10 level gives you a healthy heart and well-functioning muscles


The researchers used simple exercise tests to determine how well the study participants could perform a variety of daily activities. For example, these tests required the study participants to get up from a chair, sit down and stand up again in half a minute as often as possible [30-s chair stand], or walk as many steps as possible for 2 minutes [2-min step test].

Based on the results of the tests, the researchers divided the study participants into a group with a high risk of losing strength and muscle function due to aging, and a group with no increased risk.

When the Spaniards subsequently measured the Q10 levels of the study participants, they again saw higher Q10 concentrations in the blood of the study participants in the No Risk groups.


Over 65? A high Q10 level gives you a healthy heart and well-functioning muscles


Again, it was mainly women who seemed to benefit from a positive effect of a relatively high Q10 level. To be honest, the researchers don't know whether this is really the case. 47 of their study participants were female, 17 male. Perhaps the Spaniards couldn't find any statistically significant differences in the men because the group was simply too small.

Conclusion
"Further studies are needed to determine whether CoQ10 can also reduce this phenotype in muscle, since in the case of a positive relationship CoQ10 could be considered a senolitic compound for muscle", the researchers write.

Source:
Antioxidants (Basel). 2022 Jan 29;11(2):279.

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