Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
Do vitamin C and arginine enhance each other's antiviral effect?
Just as zinc and quercetin enhance each other's antiviral effect, L-arginine and vitamin C may enhance each other's protective effect in the context of coronavirus infection. We wrote that a few days ago. A recent Serbian in vitro study tells how. At first glance, at least...
There is some evidence that vitamin C speeds up the recovery from Covid. The same goes for arginine. That is why the Serbs wondered whether the combination of those two substances accelerate each other's antiviral effect by inhibiting 3CLpro.
The first figure below refers to vitamin C, the second to arginine.
There is a catch though. Most tested concentrations are higher than you would normally find in a human body.
We have tried to indicate them with gray bars in the figures above. The inhibitory effects you see in the table above are considerably higher than you can expect in the real world.
Supplementation may allow higher doses in some tissues than the concentrations you see above. But the concentrations at which the Serbs achieved the most promising results are probably not possible with supplementation either.
In the study we read the day before yesterday, the combination of supplementation with vitamin C and L-arginine accelerated the healing of long Covid. Perhaps this is because a relatively small effect on 3CLpro is also relevant. Or perhaps co-supplementation with vitamin C and L-arginine also works in a different way than by inhibiting 3CLpro.
We'll go over this some more... More coming soon.