Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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24.06.2022 |
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Is curcumin acetylsalicylate a life extender?
A new generation of anti-aging nutri-chemicals may soon appear on the gray market. They will have structural formulas parts of which will look familiar to you. We come to this conclusion after reading a study that researchers from Hunan University of Chinese Medicine published in Molecules. In their publication, the authors introduce the first of this possible series to us: curcumin acetyl salicylate.
Study
We have written about curcumin dozens of times. Our pieces on this miracle phytochemical can be found here.
Aspirin is an inhibitor of COX enzymes and therefore - we are cutting biochemical corners here - an inhibitor of inflammatory reactions and the formation of blood clots. In healthy people, long-term administration of aspirin has no positive health effects to our knowledge.
Both substances, curcumin and aspirin, are interesting of course. But what kind of substance do you get when two such interesting substances are glued together? What are the health effects of aspirin curcumin ester?
With tests on the worm Caenorhabditis elegans, a popular model organism in anti-aging research, a group of creative Chinese researchers tried to formulate an answer to this question.
Life extension
Mechanism
Curcumin acetylsalicylate probably stimulates the activity of genes such as daf-16. People have a number of different versions of that gene. We call them FOXO. FOXO genes initiate repair processes in cells.
Conclusion
"Nevertheless, our study has opened a new avenue to develop novel anti-aging drugs."
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