Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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18.01.2020 |
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2-oxa-methyldienolone, a forgotten super steroid
Killer drug
For a few years, methyltrenbolone was the strongest anabolic steroid that people had ever made. And still, if you are asking a well-informed anabol expert what exactly is the very strongest anabolic steroid science has ever created, he will probably mention methyltrenbolone.
If you limit yourself to steroids that have been tested on people, this answer is correct. But in 1969, two researchers from the American pharmaceutical company Searle, published an animal study which introduced an anabolic steroid that knocked methyltrenbolone off its throne.
Dienolones
As you can see, dienolone or Compound I had slightly more anabolic and slightly less androgenic effects than methyltestosterone. Methyldienolone aka Compound II was already a lot more powerful, and had 6 times more androgenic effects than methyltestosterone, and 80 times more anabolic.
The table below has been simplified. Click on it for an integral version.
However, the most interesting steroids that the researchers tested were compound III and IV. These anabolics did not have a carbon atom at the C2 position in their skeleton, but an oxygen atom. For convenience, we call these two steroids 2-oxa-dienolone and 2-oxa-methyldienolone.
The substitution caused the androgenic and anabolic effect of 2-oxa-dienolone [Compound III] to exceed that of methyltestosterone by a factor of 6 and 93, respectively.
Conclusions
"Recently, methyltrienolone [17 alpha-methyl-4,9(10),ll-trien-17-beta-ol-3-one] was also reported to have very high myotrophic activity, [Ann Endocrinol (Paris). 1965;26:95-101.] but it lacked the high degree of preferential stimulation of the levator ani muscle that was characteristic of the 17a-methyl-2-oxa derivative (IV)."
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