What kind of anabolic steroid is methyldiazirinol?
Some years ago we became fed up with all those occult anabolic steroids. So many of those $%*&^#-things popped up that we could not afford the trouble to properly investigate them. But this week, when we came across a jar with the intriguing designer steroid methyldiazirinol - aka 3,3-azo-17-alpha-methyl-5-alpha-androstan-17-beta-ol - we made our way to the library anyway.
Methyldiazirinol [chemical structure] hit the market in 2013. It is or was the active compound in Iron Legion's Triumphalis - no idea whether this product is still available. At the moment we see it mainly in products with stacks of several oral occult anabolic steroids. Producers recommend that methyldiazirinol should not be used for more than 5 consecutive weeks.
Based on wat we read on the boards, methyldiazirinol is an effective oral anabolic steroid. Quite a number of users experience serious side effects thought. Well, that's wat you can expect of this kind of 17-alpha-methylated substances.
In 1965, chemists from the American Lederle Laboratories, part of the American Cyanamid Company, published an article in the Journal of the American Chemical Society in which they introduced a group of diaziridine and diazirine steroids that they made and studied in their lab. Two of the substances that the researchers synthesized in the eraly phases of their research are shown below.
In animal studies steroid 1 was androgenic but not very anabolic, and steroid 2 anabolic but not very androgenic. When the researchers mofified steroid 2, they synthesized 3,3-azo-17-alpha-methyl-5-alpha-androstan-17-beta-ol aka methyldiazirinol.
Below you can see how Julius Vida described methyldiazirinol in his Androgens & Anabolic Agents. Vida drew from the animal studies described in the publication of Lederle Laboratories.
Methyldiazirinol had 20 percent of the androgenic effect of methyltestosterone, and 300 percent of its anabolic effect.
That's nice, of course. But this does not mean that methyldiazirinol is therefore 'a safer anabolic' than methyltestosterone. A noticeable liver destroyer as methasterone was also a beautiful anabolic product, according to animal data.
According to write-ups that you can find on the web, Lederle researchers would have already acquired a patent on methyldiazirinol in the 1950s. However, we have not been able to locate this patent. To be honest, we don't think it exists.
Methyldiazirinol has never been tested on humans. The Lederle study is the only study in which researchers have looked at this steroid.
J Am Chem Soc. 1965 87(12):2665-71.
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