This is what happens if you take 15 mg oxandrolone every day for 5 days
We don't have exact figures, but we get the feeling that over half of the chemical bodybuilders around these days are taking steroids pretty much continuously. A high-dose round of steroids is followed up with a 'hormonal recovery period' during which they use 'mild steroids' that don't 'supress endogenous testosterone production'. Oxandrolone or something like that. It's a shame most of these steroids users aren't aware of the study that American endocrinologist Melinda Sheffield published in 1999 in the Journal of Clinical Endocrinology and Metabolism.
Many steroids manuals say that oxandrolone does not supress the body's own production of testosterone. The information in these manuals is based on evidence from studies – but ones that have looked at the effects of medical dosages.
Sheffield gave 6 male students 15 mg oxandrolone every day for 5 days.
In the 1960s and 70s male bodybuilders commonly took doses of 20-30 mg per day for periods of 8 weeks. Nowadays many pharmacological bodybuilders prefer to use steroids non-stop, and some of them use oxandrolone between high-dosed rounds in the belief that their body can 'recover' on a 15-25 mg daily dose.
In the samples of muscle tissue taken after oxandrolone had been administered the participants' protein synthesis was higher than it was in the muscle tissue taken before administration of oxandrolone started.
The number of androgen receptors in the muscle cells had increased, as the figure below shows. Muscle cells manufacture more androgen receptors when the concentration of androgens in the blood is higher.
The figure above shows that the total testosterone level had decreased by almost 40 percent on day 5.
Hormonal recovery between two hefty rounds of steroids just by taking a bit of oxandrolone? Don't kid yourself.
J Clin Endocrinol Metab. 1999 Aug;84(8):2705-11.
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