Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
|
|
||||||||
09.05.2021 |
|
Take berberine, live 80 percent longer
If you respond just as well to berberine as lab mice, you can extend the number of years you are allowed to walk around this planet by 80 percent. No, that doesn't mean that berberine will prevent you from being abducted by aliens and sold into slavery on another planet. Berberine extends life. That's all.
Berberine
Study
Results
As the brains of mice age, their coordination capacity diminishes. They are more likely to tumble from a spinning rod. However, if the mice from above were given berberine, their coordination capacity remained stable. You can see this above.
These experiments suggest that berberine increases health span.
In another series of tests, the researchers were able to show that berberine also extended the life span. When mice at 18 months were given berberine for 4 months, the number of days they could still live increased by as much as 80 percent.
The human equivalent of the dose tested was again about 400 milligrams per day.
A molecular marker of aging is the activity of the enzyme senescence-associated beta-galactosidase. Medicines such as doxorubicin make that enzyme more active. At the bottom right you can see that berberine reduces the increase in the activity of senescence-associated beta-galactosidase by doxorubicin.
Conclusion
"Therefore, this molecule may be a candidate as an anti-aging drug for the treatment of age-related diseases that are, at least in part, driven by senescence."
Source: More: Archives:
|
|