Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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21.07.2025 |
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Getting enough selenium slows down the rate of your aging
If you get enough selenium - which isn't a given in most countries - you age more slowly than if your intake is too low. This is suggested by a German molecular epidemiological study published in Clinical Epigenetics.
Study
The researchers excluded users of selenium supplements from their study.
These white blood cell analyses focused on the methylation of genes in the DNA of those cells. The more a cell ages, the more methyl groups are attached to these genes. They often no longer function properly.
The researchers used various computational models to express the methylated genes in aging. These models have names such as DunedinPace, Horvath, Hannum, PhenoAge, GrimAge, and 7-CpG. Scientists prefer to call these computational models epigenetic clocks.
Results
The DunedinPace model is a third-generation epigenetic clock. It was created by an AI that linked methylated genes to symptoms of aging, such as tooth loss, decreased lung function and muscle strength, and cognitive decline.
The figure below shows that a higher GPX3 concentration is associated with slower aging according to the DunedinPace epigenetic clock—not according to other clocks. Click on it for a larger version.
If we do a calculation that's not entirely consistent with the rules, someone who has had a good selenium status for 30 years [Q4] would be 1.1 years younger biologically than someone who has had a poor selenium status for 30 years [Q1].
Conclusion
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