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02.06.2023


Higher magnesium intake, less liver cancer

If you drink alcohol - and perhaps if your lifestyle is otherwise stressful on your liver - a relatively high intake of magnesium reduces your risk of liver cancer.


If you drink alcohol - and perhaps if your lifestyle is otherwise stressful on your liver - a relatively high intake of magnesium reduces your risk of liver cancer.


Study
Hepatologists at Vanderbilt University in the US analyzed data from more than half a million retired Americans collected by the National Institutes of Health.

The study participants had completed questionnaires about their diet and told about their health.

Based on their magnesium intake, the researchers divided the study participants into 4 equally sized groups [quartiles]. They then brushed off the effect of other factors as far as possible and determined the risk of liver cancer for each quartile.

Results
A total of 1067 study participants reported liver cancer.

In the quartile with the highest intake of magnesium - more than half a gram per day - the risk of liver cancer was 35 percent lower than in the quartile with the lowest magnesium consumption - less than 290 milligrams of magnesium per day.

Click on the tables below for a larger version.


If you drink alcohol - and perhaps if your lifestyle is otherwise stressful on your liver - a relatively high intake of magnesium reduces your risk of liver cancer.


If you drink alcohol - and perhaps if your lifestyle is otherwise stressful on your liver - a relatively high intake of magnesium reduces your risk of liver cancer.


When the researchers looked at the alcohol users separately, they saw that a high magnesium intake reduced the risk of liver cancer in that group - and not in the group of alcohol abstainers.

Apparently magnesium is a protective factor in a lifestyle that puts a strain on the liver. It wouldn't surprise us, the industrious compilers of this free web magazine, if a study ever appears in which users of oral anabolics or SARMS develop liver problems less often if they consume a lot of magnesium.

Just a random example.

Mechanism
The researchers pay little attention to how magnesium could reduce the risk of liver cancer. They do cite a few reviews speculating about possible anti-cancer effects of magnesium. Those reviews emphasize that magnesium inhibits inflammation and is involved in repair processes of the cell's hereditary material. [Rocz Panstw Zakl Hig. 2013;64:165-71.]

Source:
Am J Clin Nutr. 2021 Mar 11;113(3):630-8.

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Archives:
Magnesium
Minerals
Liver


Low magnesium levels will kill you Magnesium lowers cortisol levels Magnesium is an antidepressant

Low magnesium levels will kill you
Japanese epidemiological study.

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Clinical data from The Netherlands.

Magnesium is an antidepressant
Daily supplementation with 250 mg elemental magnesium can help relieve mild depression.