Do NO boosters inhibit the coronavirus?
The NO boosters used by fitness fanatics and bodybuilders may protect against the dreaded coronavirus. This is suggested by an in vitro study published by the Swedish microbiologist Dario Akaberi, affiliated with the University of Uppsala, in Redox Biology.
Akaberi released the coronavirus onto epithelial cells in his lab and then watched the virus multiply.
The researcher also exposed some cells to S-nitroso-N-acetylpenicillamine [SNAP] at the same time. S-nitroso-N-acetylpenicillamine is a NO donor. Akabari did not experiment with the substances that you can find in NO boosters, but with a substance that does the same.
The higher the concentration of S-nitroso-N-acetylpenicillamine, the slower the coronavirus was able to multiply.
Each spot in the circles above is a cell that is no longer functioning properly due to the virus.
The figure below shows how NO boosters inhibit the virus. S-nitroso-N-acetylpenicillamine sabotages the protease enzyme. After having infected a cell, a virus needs protease to multiply itself.
NAP = non S-nitrosated N-acetylpenicillamine. Say: SNAP, but without an NO group to donate. A bit straightforward, but fine.
"We conclude that NO may be applied for clinical use in the treatment of COVID-19 and other human coronavirus infections", the Swedes conclude.
Redox Biol. 2020 Sep 21;37:101734.
Vitamin D deficiency reduces survival after coronavirus infection 21.08.2020
Vitamin D may be a Covid-19 drug, American study suggests 04.05.2020
After infection with the coronavirus, a high vitamin D level may prevent you from getting sick 24.04.2020