Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
Dioscorea esculenta increases the concentration of DHT in muscles
The researchers, who are affiliated with Ritsumeikan University, experimented with OLETF rats. This is a type of lab rat that spontaneously develops type-2 diabetes. [Diabetes Res Clin Pract. 1994 Oct;24 Suppl:S317-20.]
During the 8 weeks that the experiment lasted, the researchers did nothing at all with the first group of rats. This was the control group. [Con]
A second group of rats ran on a treadmill 5 days a week. [Ex]
A third group of rats were given feed in which the researchers had put a concentrated yam powder. If the rats had been adult humans, they would have been fed 40-60 grams of yam powder daily. [Dio]
A fourth group of test animals also received dutasteride in addition to yam powder. Dutasteride is a steroid that blocks the biosynthesis of DHT in the body. [Dio + in] Previous studies had already shown that DHT plays a role in the health effects of yam.
Dioscorea esculenta, a variety that also occurs in the wild and is cultivated in countries such as Japan, contains 200 times more diosgenin than other yam varieties.
By the way, Takara did not sponsor the study. The researchers were funded by the Japanese government.
Dioscorea esculenta also lowered the glucose level, and this effect was absent in the rats that received dutasteride.
In a way that we cannot properly explain, Dioscorea esculenta increased the concentration of DHT in the blood, as well as in the muscles of the rats. And, as you would expect, dutasteride reversed this effect.
Would Dioscorea esculenta also have such beautiful effects in human studies?