ergo-log.com

Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "

15.11.2024

Diabetic foot ulcers may heal faster with magnesium supplementation

Not only vitamin C supplementation may accelerate the healing of diabetic foot ulcers. According to a - not entirely uncontroversial - trial from 2018, supplementation with magnesium may have the same effect.

Study
In 2018, doctors from Kashan University of Medical Sciences in Iran published a small trial in Biological Trace Element Research. In that trial, 35 subjects with diabetic foot ulcers received a supplement with 250 milligrams of magnesium in the form of magnesium oxide every day for 12 weeks, while another 35 comparable subjects received a placebo.

The researchers used a supplement from the American 21st Century Pharmaceutical Company. By the way, the product also contains a negligible amount of calcium.

In 2020, the editors of Biological Trace Element Research announced that questions had arisen about 'the integrity of the clinical trial reported here'. The Iranian National Committee for Ethics in Biomedical Researches was reviewing the research, the editors wrote. Because there has been no clarity for four years now, we decided to write a post about this trial.

Regardless of the outcome of this inquiry, there are indications that magnesium does play a role in the healing of diabetic foot ulcers. In epidemiological studies, researchers find a lower concentration of magnesium in the blood of patients with foot ulcers. [Pak J Med Sci. 2013 Nov;29(6):1329-33.] [Arch Med Res. 2001 Jul-Aug;32(4):300-3.]

Results
The depth, length and width of the foot ulcers decreased in both groups, but the decrease was at least twice as great in the supplementation group.

Mechanism
Magnesium supplementation caused several mild positive health effects. In the blood of the subjects in the experimental group, the concentration of the inflammatory factor hCRP fell, the effect of insulin seemed to improve and the activity of antioxidants increased.

The researchers suspect that all these factors together led to accelerated healing of foot ulcers.

Combination
Daily supplementation with half a gram of vitamin C per day also accelerates the healing of diabetic foot ulcers. Perhaps magnesium works even better in combination with a substantial dose of vitamin C.

Source:
Biol Trace Elem Res. 2018 Feb;181(2):207-15.

More:
Vitamin C supplement accelerates foot ulcer healing 07.12.2022

Archives:
Magnesium
Minerals

Thymogen accelerates healing of wounds in diabetics, improves sports performance as well? For years, Russian doctors have used the dipeptide Thymogen, which is available on the gray market in the West. According to a 2019 patent, Thymogen accelerates the healing of diabetic foot ulcers.	Wounds heal faster with proline You can probably speed up the process of healing a wound by taking a supplement containing the amino acid L-proline.	Wound heals faster by supplementing with arginine, vitamin C and zinc This is shown by a small human Australian study, in which patients with pressure ulcers were used as test subjects.