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12.08.2023


In surprisingly small amounts, Aloe vera sterols improve skin

Aloe vera contains sterols. These compounds have a stimulating effect on skin cells. Their effect is so strong that supplementation with just 20 micrograms per day improves skin elasticity and hydration.


In surprisingly small amounts, Aloe vera sterols improve skin


Study
Japanese dermatologists at Wakayama Medical University divided 122 women aged 30-54 into 2 groups. For 12 weeks, one half took a placebo every day, while the other half took 2 capsules containing an aloe vera extract.

The extract was produced by the Japanese food company Morinaga. Although the article does not mention funding, it is clear that Morinaga had a hand in the research. 4 employees of Morinaga's R&D department were co-authors.

The subjects in the experimental group took 500 milligrams of extract every day. These were extracted from the plant with supercritical carbon dioxide and contained a total of 20 micrograms of sterols, such as lophenol, 24-methyl-lophenol, 24-ethyl-lophenol, cycloartanol and 24-methylene-cycloartanol.


In surprisingly small amounts, Aloe vera sterols improve skin


Results
The researchers used ultrasonic technology to determine the thickness of the women's skin. In this way they determined the amount of collagen in the skin. The skin collagen score of the women in the experimental group increased significantly.


In surprisingly small amounts, Aloe vera sterols improve skin


In surprisingly small amounts, Aloe vera sterols improve skin


Aloe vera sterol supplementation had no effect on wrinkles.

The supplement also had no effect on the hydration of the skin - measured with a corneometer that sends currents through the skin. However, the latter was the case when the Japanese only looked at women with dry skin. In that subgroup, Aloe vera sterols statistically significantly increased hydration.

Click on the table below for a larger version.


In surprisingly small amounts, Aloe vera sterols improve skin


In surprisingly small amounts, Aloe vera sterols improve skin


Mechanism
In 2015, researchers at Morinaga published an in vitro study in which human skin cells produced 2 and 1.5 times more collagen and hyaluronic acid, respectively, when exposed to Aloe vera sterols. [Clin Cosmet Investig Dermatol. 2015 Feb 20;8:95-104.]

Morinaga then tested the effect of 40 micrograms of sterols in human research - with good results. [Skin Pharmacol Physiol. 2016;29(6):309-17.] Half of that dose apparently also works fine, we now know.

Source:
J Dermatol. 2020 Sep;47(9):998-1006.

More:
Aloe vera is an aphrodisiac 26.06.2019
Aloe vera as a slimming supplement 03.04.2015

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