Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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18.10.2011 |
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Animal study: Royal Jelly has life extending properties
Royal Jelly boosts testosterone levels, and this happens partly through an anti-aging mechanism in the pituitary, we wrote a few months ago. As chance would have it, in 2011 PLoS published the findings of a Japanese study on the life-extending effects of Royal Jelly. Ok, only in nematodes - but you've got to start somewhere.
Royal Jelly
But it's not the fault of the researchers: the composition of Royal Jelly is complex. Analyses have shown that Royal Jelly contains at least the following components: proteins, peptides, free amino acids, sugars, vitamins, acetylcholine and other interesting compounds including AMP-N1-oxide and the fatty acid 10-hydroxy-2-decenoic acid [10-HAD], of which the structural formulas are shown below.
Study
Results
Then the researchers tested their preparations again, but after they had treated them with protein-splitting enzymes. The Royal Jelly still worked, which means that the life-extending substances were not proteins or peptides. So was it a fatty acid that was responsible? Maybe the 10-hydroxy-2-decenoic acid? Royal Jelly consists of 1.7 percent 10-hydroxy-2-decenoic acid, so that might be the case.
The Japanese repeated their experiment using this compound. And lo and behold.
The researchers tried to measure genes and introduce mutants in order to unravel the mechanism through which Royal Jelly works, but did not obtain conclusive evidence.
Conclusion
Source:
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