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Optimal fish oil dose depends on body weight

If for any reason you use fish oil and discover that it's not working after a couple of weeks, it may be because you're overweight. The heavier you are the more slowly the concentration of omega-3 fatty acids rises in your body. American psychiatrists at the Ohio State University discovered this when they got young people to take fish oil capsules.

The researchers gave 28 young people aged between 7 and 14, all of whom suffered from mood disorder, four fish oil capsules per day for 12 weeks. They used a product made by the American OmegaBrite. [] Each capsule contained 350 mg EPA, 50 mg DHA 100 mg of other omega-3 fatty acids. So the subjects took 2 g omega-3 fatty acids per day.

The more the participants weighed, the less increase there was in the concentration of EPA and DHA in their blood.

Optimal fish oil dose depends on body weight

Optimal fish oil dose depends on body weight

"The current study demonstrates clear linear relationships of both body weight and BMI with plasma omega-3 PUFA accumulation in children and adolescents," the researchers concluded. "These data did not show that clinical overweight or obesity were particularly predictive; rather, a dose-response effect was observed across the BMI spectrum."

"Guidelines for optimal omega-3 PUFA intake in youth should consider using weight rather than age-based determinations."

"Studies examining potential clinical effects of omega-3 PUFAs in youth as well as adults should incorporate the effects of weight into statistical models, as weight-related differences in effects may contribute meaningfully to inconsistencies in the current literature."

PLoS One. 2017 Apr 5;12(4):e0173087.

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Fish Oil

DHA combined with exercise protects brain against knocks
Animal study, published in Neuroscience.

Daily capsule of phosphatidylserine-DHA-complex improves memory in over 60
According to the manufacturers they protect the brain from the effects of aging. At first glance, these human studies would seem to confirm this claim.

Fish oil increases insulin sensitivity only when combined with exercise
Epidemiologists at the University of Pittsburgh in the US have probably discovered the reason why different studies come to different conclusions.