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31.03.2022

Oligonol, the lychee supplement that protects against heart attacks

Oligonol, a lychee-based supplement that has been shown to inhibit muscle breakdown in animal studies and increase endurance in human studies, protects against strokes and heart attacks, and perhaps also against diabetes.

Oligonol
Oligonol is a product of the Japanese Amino Up. [aminoup.jp] Amino Up obtains the raw materials for Oligonol from the skins of lychees, and not from the fruit itself. That also makes it difficult for us to calculate how many lychees you need to match the effects of supplementation.

Amino Up supported the authors of the study we are now discussing with supplements, placebos, and hard-to-find chemicals. As far as we can determine, there was no question of full blown sponsorship.

Study
Biochemists from King Abdulaziz Saudi University in Saudi Arabia divided 47 fat but healthy women into 2 groups. For three months, the subjects in one group took a placebo every day [group A], while the subjects in the other group took two capsules of Oliginol daily with a meal [group B].

The researchers do not mention dosages, but we suspect that they used a product that contained 100 milligrams of extract per capsule.

Results
The researchers found indications for a limited effect on body composition. The women in the Oligonol group lost just under a kilo of body weight, but on the other hand, the women in the placebo group gained over a kilo. The researchers had hoped for more, you can read between the lines.

Oligonol lowered the concentration of triglycerides in the blood by 17 percent. Triglycerides are usually found in the 'extremely unhealthy cholesterol' VLDL. This shift suggests that Oligonol protects against vascular disease, stroke and heart attacks.

Click on the table below for a larger version.

Oligonol lowered the concentration of resistin in the blood. That may imply that oligonol reduces the risk of type-2 diabetes.

Conclusion
"Oligonol has potential in combating the obesity epidemic in Saudi Arabia", resume the Saudis.

"Dietary restriction and/or increased physical activity in addition to Oligonol might lead to more weight loss than is achieved without the supplement."

"Future studies should focus on this latter point, along with characteristics of best responders."

Source:
Curr Nutr Food Sci. 2018 Apr; 14(2):164-70.

More:
Oligonol, a muscle-building supplement based on lychees 25.03.2022
Lychees inhibit muscle breakdown | Animal study 22.03.2022
Lychee extract boosts athletes' endurance capacity 09.03.2014

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