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29.09.2021


Carnitine reduces autism

Supplementation with a very reasonable dose of L-carnitine can alleviate autistic symptoms. This is apparent from an older American trial, which was published in 2011 in the Medical Science Monitor.


Carnitine reduces autism


Study
The researchers experimented with 30 boys aged 3-10, all of whom had been diagnosed with some form of autism.

Some of the boys received a placebo daily for 3 months, while others received a liquid carnitine supplement. The boys were given 50 milligrams of L-carnitine per day per kilogram of body weight.

Before and after the supplementation period, the researchers determined the degree of autism of the victims using the Childhood Autism Rating Scale (CARS).

The researchers suspect that autism may be related to mitochondria in brain cells that do not function optimally. They hope that supplementation with carnitine can reduce that deficiency.

Results
Carnitine reduces autism
The average CARS score in the carnitine group dropped from 35.7 by almost 2 points to 33.8. When supplementation started, the average CARS score of the boys in this group was in the mild-moderate part of the autism spectrum.

When the supplementation period was over, the average score was still in the mild-moderate part of the autism spectrum.

The table and the figures below have been reduced or simplified. Click on them for a larger or full version.


Carnitine reduces autism

Carnitine reduces autism


The greater the increase in the concentration of unbound carnitine in the boys' blood, the greater the improvement in the scores.

The researchers also determined how much force the boys could use to squeeze a dynamometer with their hands. The boys' hand grip strength increased by supplementing with carnitine.


Carnitine reduces autism


Conclusion
"It is suggested that future studies further explore additional dosing regimens to identify the potential optimal dosing level or range of L-carnitine for subjects diagnosed with an autism spectrum disorder", write the researchers.

Source:
Med Sci Monit. 2011 Jun;17(6):PI15-23.

More:
Sulforaphane supplement mitigates autism traits 08.02.2015
L-Carnitine reduces ADHD symptoms 01.03.2014

Archives:
L-Carnitine


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