Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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07.09.2012 |
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Weight loss faster with alpha-lipoic acid
Alpha-Lipoic acid is not a vitamin. Our cells make the substance themselves and only minute quantities are found in our food. The mitochondria, the cellular power stations, need alpha-lipoic acid to convert nutrients into energy. If you give alpha-lipoic acid to lab animals their energy expenditure rises and they lose weight. Whether humans react in the same way to supplementation had not been studied.
One-third of the test subjects took a daily total of 1200 mg alpha-lipoic acid, spread over three intake moments throughout the day, each half an hour before a meal.
A second group did the same but took 1800 mg alpha-lipoic acid daily. A third group was given a placebo.
The supplement speeded up weight loss, as the figure below shows. In the group that took 1800 mg alpha-lipoic acid per day the effect was statistically significant.
Animal studies suggest that weight loss through alpha-lipoic acid is gained at the cost of lean body mass, but that was not the case in this human trial. The test subjects lost a small amount of lean body mass, but not more than you’d expect in a dieting study.
"Although the therapeutic potency of alpha-lipoic acid was modest, no serious side effects were observed", the researchers conclude. "Differences in side effects from currently used anti-obesity drugs suggest that alpha-lipoic acid may be effective as an adjunctive medication for obesity."
The Korean government – in the form of the Korea Health Industry Development Institute – and Dalim BioTech funded the study. Dalim Pharm produces supplements, some of which contain alpha-lipoic acid.
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