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Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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17.05.2020 |
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Sometimes SARMs damage the liver
Like anabolic steroids, SARMs accelerate muscle growth, but without the side effects associated with the use of anabolic steroids. Unlike oral steroids such as methandienone and oxymetholone, SARMs do not damage the liver. At least, that's what the sellers of SARMs claim. Still, Australian MDL doctors in Hepatology Communications describe two cases of liver damage in men who had used the SARMs RAD140 and LGD4033.
RAD140
After the man developed jaundice and itching, he sought medical attention. Analysis of his blood showed that the concentration of enzymes, which indicate that the liver is damaged, was increased. The analysis suggested the man suffered from cholestasis, a classic side effect of using oral anabolic steroids.
The doctors stopped the man from taking his medicines and gave him ursodiol and cholestyramine. His liver recovered in the months that followed. A year later, all his values were back to normal.
Click on the figure below for a larger version.
LGD4033
The man had become ill a week after his cycle had ended, but only after 3 weeks did he see a doctor. He had jaundice, was nauseous, barely ate and had already lost 5 kilos.
The man was not using any other means. However, he failed once a month, and then consumed a lot of alcohol. In his blood, the researchers found an increased concentration of enzymes that indicate liver damage. The man's liver was enlarged, but according to a scan, there was no evidence of decreased drainage of bile salts.
The researchers decided to wait and saw that the liver had recovered 4 months later.
Click on the figure below for a larger version.
Conclusion
"Whether these cases represent the tip of the iceberg remains to be seen, but given the increasing popularity of SARM use, greater vigilance and reporting of potential cases is required."
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