Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
Oxandrolone can reverse effects of muscle disease
Hold on a moment. Who said anabolic steroids no longer have any medical uses? You? Well, that means lines for you young man. "According to Italian neurologists, oxandrolone is an anabolic steroid that can help in the treatment of the muscle disease Charcot-Marie-Tooth." Write out a thousand times and hand it in tomorrow.
In MS it is the cells in the brain and spinal column that are affected. MS is a more aggressive disease than Charcot-Marie-Tooth. People with MS have a life expectancy that is five to ten years shorter than healthy people; Charcot-Marie-Tooth does not decrease life expectancy.
There are different forms of Charcot-Marie-Tooth. The subject that the Italians used, a 25-year-old man, had CMT-1. The researchers described his state as "a severe demyelinating neuropathy presented with spastic tetraparesis, muscle weakness, spasticity, and instability during deambulation."
The man took 20 mg oxandrolone daily [structural formula shown on the right]. In addition he was given an injection of 2000 units hCG every two weeks. This was intended to maintain his own testosterone synthesis.
The speed at which the muscles transmitted signals to the muscles increased by 9 percent; the strength of the signals travelling from the brain to the muscles increased by 10 percent.
At the end of the oxandrolone and hCG course, the researchers noticed that strong type-2 muscle fibres had started to cluster in the subject's muscle tissue. The Italians regard that as "an expression of regeneration and reinnervation processes".
"This observation suggests that treatment with oxandrolone may be useful to restore functional axon and motoneuron efficiency and could be considered within rehabilitation programs in patients with neuromuscular damages, such as demyelinating diseases, hereditary neuropathy, aging, and after peripheral injury."
The researchers' confidence in androgen therapy seems also to be confirmed by the experiences of other patients which they describe in the conclusion of their article. "We have treated other patients with similar diseases and paraplegic subjects after spinal cord injury and in our experience, all patients benefit from androgen therapy."
"The aim of this study is to increase the interest to other authors in further research because studies in this field are clearly warranted and useful for clinical practice", the researchers concluded.