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Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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29.12.2010 |
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Fat belly neutralises DHT
Those spare tyres around the middle are even worse for men's androgen levels than we thought. Enzymes in fat tissue not only convert testosterone into estradiol, but also transform the androgen DHT into inactive compounds.
But fat men who put all their faith in testosterone therapy and do not try to lose weight may be making the wrong choice. The more fat men carry, the less they react to testosterone therapy. And what's more, fat men are also more likely to develop side-effects from testosterone therapy.
The researchers examined pieces of subcutaneous fat and abdominal fat from fat and thin men. They discovered that especially in subcutaneous fat there is a high level of conversion of DHT into 5-alpha-androstane-3-alpha,17-beta-diol. The enzymes that activated DHT were more active in mature fat cells [mature adipocytes] than in fat cells that had not yet reached maturity [pre adipocytes].
So the more fat you have, the more DHT is deactivated in your body. But that's not the whole story, as you can see directly above here. If men put on weight, then by kg bodyweight, the DHT deactivating enzymes become more active.
For keen strength athletes who could do to lose a bit of fat, the take home message is clear.
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