Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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11.08.2015 |
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Steroids, creatine and high-protein diet can cause kidney damage if you don't drink enough
Steroids, proteins and creatine
All of the bodybuilders used anabolic steroids, including nandrolone decanoate and testosterone propionate, which they injected. The researchers do not reveal the exact dosages, but say that the men had been injecting themselves with more than 400 mg of steroids each week.
In addition, the men had been taking protein supplements and creatine. They consumed 78-104 g protein a day. In total the men consumed 3.2-4.2 g protein per kg bodyweight per day. And on top of that the men took 15 g creatine every day.
Kidney damage
Kicking the habit
Normal creatinine levels for men are between 60 and 110 micromoles per litre.
A measurement that gives much more information is the estimated glomerular filtration rate. The lower this is, the less blood the kidneys are able to filter and clean. The bodybuilders' estimated glomerular filtration rate at the beginning was 22-34 millilitres per minute. That's an alarmingly low level, as the table below shows.
Possible explanation
"There is concern that excess dietary protein and creatine that is not accompanied by increased fluid intake may lead to a relative hypovolemia", the researchers wrote. "The clinical presentation of our three of our patients was in the summer. Iraqi summers are very hot, and by Western standards, the regional gymnasiums are warm and trainee hydration less than optimal."
"We must emphasize that a specific offending agent cannot be identified in this case material, and it may be the combination of excess creatine and protein with steroid injections that compounds risk not incurred with the individual substances."
"Our working hypothesis is that under hydration rather than direct toxicity precipitated the kidney injury."
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