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06.09.2013


Do you sleep badly in the summer? Maybe ornithine can help

Many people have difficulty sleeping in the summertime. This probably happens because the longer day length makes us more active. Japanese researchers at the University of Kagoshima and the amino-acid manufacturer Kyowa Hakko Bio published the results of a study which you can interpret as suggesting that ornithine supplementation may offer some help.
Many people have difficulty sleeping in the summertime. This probably happens because the longer day length makes us more active. Japanese researchers at the University of Kagoshima and the amino-acid manufacturer Kyowa Hakko Bio [kyowahakko-bio.co.jp] published the results of a study which you can interpret as suggesting that ornithine supplementation may offer some help.

Ornithine & sleep
Kyowa Hakko is part of Kirin, a division of Mitsubishi. Within the Kirin Holdings Company a Functional Food Business Project developed an interest in the effects of ornithine on sleep. For example, the project was involved in a human study that was published in spring 2013 in BioPsychoSocial Medicine [Biopsychosoc Med. 2013 Feb 18;7(1):6.], in which researchers studied the effect of ornithine on sleep after alcohol use.

Study
Many people have difficulty sleeping in the summertime. This probably happens because the longer day length makes us more active. Japanese researchers at the University of Kagoshima and the amino-acid manufacturer Kyowa Hakko Bio published the results of a study which you can interpret as suggesting that ornithine supplementation may offer some help.
The researchers got their subjects to drink alcohol in the evening, and then gave them a capsule containing 400 mg ornithine or a placebo. They discovered that the amino acid reduced the concentration of the stress hormone cortisol the following day. In the figure on the right the black bars represent the subjects who had taken ornithine.

Results
The researchers used a standardised questionnaire to ascertain from the subjects the following day how well they had slept. The ornithine users reported feeling significantly less fatigue than the placebo users and they also reported less lassitude.


Many people have difficulty sleeping in the summertime. This probably happens because the longer day length makes us more active. Japanese researchers at the University of Kagoshima and the amino-acid manufacturer Kyowa Hakko Bio published the results of a study which you can interpret as suggesting that ornithine supplementation may offer some help.


Another study
In July 2013 another study was published by the same group on the effect of ornithine on sleep. The subjects this time were the members of a Japanese expedition to Antarctica. They spent three months at the South Pole after arriving in December. So it was summertime there and the sun never set.

During their stay the placebo users reported that the quality of their sleep deteriorated. The ornithine users, who took 400 mg ornithine every day for two months, reported that their sleep quality remained stable. At the end of the two months they reported that their quality of sleep had actually improved.


Many people have difficulty sleeping in the summertime. This probably happens because the longer day length makes us more active. Japanese researchers at the University of Kagoshima and the amino-acid manufacturer Kyowa Hakko Bio published the results of a study which you can interpret as suggesting that ornithine supplementation may offer some help.


The researchers are still puzzling over the mechanism at work here. They suspect that the ornithine administration meant that the brain was supplied with more serotonin, but this theory was not supported by blood tests carried out on the subjects.

Arginine?
A few years ago we wrote about an experiment done by the biochemist Mohamed Gad, who gave his test subjects a nightcap of 5 g L-arginine. Arginine is a metabolite of ornithine. The subjects' health improved on all fronts: they started to feel noticeably better and reported that they slept better too.

Source:
Nutr Res. 2013 Jul;33(7):557-64.

More:
Eat two kiwis for a good night's rest 22.02.2013
Glycine boosts reaction time with lack of sleep 19.02.2013
Improve your sleep with glycine, and your memory will work better too 18.02.2013

Archives:
Amino Acids
L-Ornithine
Sleep


Athletes' reaction times improve with BCAA-ornithine combo Ornithine strengthens mental effects of caffeine Ornithine removes ammonia from athletes' blood

Athletes' reaction times improve with BCAA-ornithine combo
A heavy dose of BCAAs and L-ornithine L-aspartate can help keep reaction times up during heavy physical exercise, and that's extremely handy for those who practise martial arts or team sports.

Ornithine strengthens mental effects of caffeine
The stimulant caffeine has more effect when combined with the amino acid ornithine write Japanese researchers in Preventive Nutrition and Food Science.

Ornithine removes ammonia from athletes' blood
Athletes who take a few grams of L-ornithine HCl an hour before training get less tired. The amino acid stops the ammonia concentration in the blood from rising.