Q10 and L-carnitine effective against migraine
Supplementation with 30 milligrams of Q10 and 500 milligrams of L-carnitine per day can drastically improve the lives of people with migraine. Researchers at Isfahan University of Medical Sciences in Iran discovered this. Their study has been published in Cephalalgia.
Migraine and supplementation
According to a popular theory, migraine is the result of malfunctioning mitochondria. Mitochondria are the cells' power plants; they convert nutrients into energy. Scientists who value this theory are experimenting with nutrients that should make mitochondria with defects work normally again. Vitamin B2, magnesium and Q10 are such substances.
In theory, supplementation with L-carnitine could improve the functioning of mitochondria. L-Carnitine plays a key role in the transport of fatty acids into the mitochondria, where the are transformed into cellular energy. The researchers decided to study the effect of L-carnitine in combination with Q10 in a human study. Q10, by the way, ensures that electrons released during the conversion of nutrients into energy do not damage the mitochondria.
According to a recent meta-study, supplementation with Q10 reduces the number of attacks of migraine, but not their severity or duration. [Nutr Neurosci. 2019 Feb 6:1-8. doi: 10.1080/1028415X.2019.1572940. [Epub ahead of print].] The effect of L-carnitine on migraine has not yet been investigated.
The researchers divided fifty people with migraine into 2 groups. One group received a placebo for 8 weeks, the other took 30 milligrams of Q10 and 500 milligrams of L-carnitine daily. The researchers used a Q10 product from Mix Natural and a carnitine supplement from Karen. You can see the latter supplement above this page.
Supplementation with L-carnitine and Q10 reduced the severity of the migraine attacks, the number of migraine attacks and their duration.
"The findings suggest that CoQ10 plus L-carnitine supplements had beneficial [...] effects on migraine symptoms in migraine patients," the researchers summarize. "Cross-over trial studies are required to further confirm these findings."
Cephalalgia. 2019 Apr;39(5):648-54.
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Headache & Migraine