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Definition: "An ergogenic aid is any substance or phenomenon that enhances performance "
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08.06.2018 |
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Physical activity enables the brain to repair itself and rejuvenate itself
If you want your brain to function as well as possible up to old age, make sure you exercise a lot. Even if you dislike physical activity, and also if you are only happy behind a computer screen or reading a book, a sedentary lifestyle is disastrous for your brain. Italian researchers from the University of Milan come to this conclusion in an animal study, which has been published in Frontiers in Neurology.
Study
The researchers also studied the subventricular zone of mice that had full control over their hind legs [Control; CTR].
Results
In the stem cells of the inactive mice, the gene Cdk5rap1 was less active. That gene is involved in keeping the mitochondria, the 'power plants of the cell' , healthy.
"The discovery that Cdk5rap1 (which acts as methylthiotransferase in mitochondria RNA) was altered in its expression after motor deprivation is very intriguing in this context, and opens a new link between neurogenesis metabolism and cell regulation", write the Italians.
In the stem cells of the inactive mice, the researchers found fewer cells that produced the protein beta-tubulin-3. As only neurons and cells in the testis produce this protein, this means that fewer stem cells developed into new neurons in the inactive mice.
Conclusion
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