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03.06.2017


Impact of long-term use of steroids in elite athletes not as serious as thought

Elite athletes who used steroids decades ago are more likely to suffer from depression, anxiety disorders and ruptured tendons - but not from cardiovascular disease. Addiction researchers at the University of Gothenburg in Sweden discovered this when they studied 683 former elite athletes. The study also suggests that steroid use reduces the chance of prostate enlargement and libido problems.

Study
The researchers questioned Swedish elite athletes who had performed sports known for their steroids use, such as powerlifting, weight lifting, wrestling, shot put and discus, between 1960 and 1980.

The researchers asked the athletes about any serious health issues they had encountered in their life.

Of the 683 athletes who had filled out written questionnaires, 143 said that they had used steroids and reported how long they had done so during their athletic career.

Results
The figure below summarises the more or less statistically significant relationships. Steroids use increases the chance of ruptured tendons, depression and anxiety disorders in the long term, but reduces - which is strange - the chance of prostate enlargement and decreased libido.


Impact of long-term use of steroids in elite athletes not as serious as thought


The most noticeable thing about this epidemiological study, however, is what the researchers didn't find. Where are the cardiovascular diseases? The strokes? The heart attacks? They are nowhere to be found. The Swedes suspect that the participants used such low doses in the 1960s and 70s that the likelihood of long-term cardiovascular health defects was minimal.

Conclusion
"Former anabolic steroids abuse does seem to have a strong association with psychiatric problems, such as depression and anxiety," the Swedes summarised.

"This association seems to be even stronger if the abuse of anabolic steroids was advanced (anabolic steroids cycles more than 2 years)."

"This result raises the question whether these somatic and mental health effects of anabolic steroids abuse are dose- and frequency dependent. However, no large differences were seen in somatic health except an association between former anabolic steroids abuse and tendon rupture, which has been noted in previous short-term studies."

"Interestingly, a former anabolic steroids abuse, especially if the abuse was not as advanced, seemed to give a lower incidence of prostate hypertrophy, which probably is explained by an anabolic steroids induced relative hypogonadism rendering a lower prostate volume, but does not readily explain the observed decreased libido problems."

"However, these findings should be seen as hypothesis generating and further studies are needed."

Source:
J Sci Med Sport. 2017 Mar 21. pii: S1440-2440(17)30337-7.

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