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09.04.2014


Why bodybuilders who still smoke should use BCAAs

Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.

Smoking, muscles & BCAAs
Smoking boosts myostatin activity in muscle cells, causing muscle degeneration. Smoking also encourages the formation of advanced glycation end products [AGEs] in the muscles, thus reducing muscle strength.

The Japanese were curious as to whether the muscle-shrinking effects of smoking were in any way related to BCAAs [structural formulas shown below]. Did smokers' muscles absorb fewer BCAAs perhaps? And if so, could smokers maintain muscle strength by taking a supplement containing BCAAs?


Leucine Valine Isoleucine

Leucine

Valine

Isoleucine


Study

To answer these questions the researchers devised an animal experiment in which one group of young rats was exposed to cigarette smoke for four weeks, and one group was not.

Of both groups, half was given standard food and the other half was given food to which BCAAs had been added. The BCAA-enriched food contained approximately the same amount of amino acids as the standard food.


Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.


Results
The rats that inhaled cigarette smoke grew less fast. That was partly because they ate less.


Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.

Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.


The BCAA supplementation did not normalise the growth rate of the smoking rats, but it did counteract the negative effects of smoking on muscle mass. The figure below shows the weight of the gastrocnemius [calf muscle] in the four groups.


Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.


The Japanese discovered that smoking reduces the concentration of BCAAs in the blood. BCAA supplementation can negate the effect of smoking and restore the quantity of BCAAs in the bloodstream.


Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.


The muscles of the animals that inhaled smoke also contained lower amounts of BCAAs. That's why their muscles were smaller than those of the other lab rats. BCAA supplementation also normalised the amount of BCAAs in the rats' muscles.


Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.


Mechanism
Smoking is bad for pretty much everything, and that includes your muscles. Researchers at Nara Medical University in Japan made an interesting discovery for bodybuilders and other strength athletes who still smoke: supplementation with BCAAs can help counteract the negative effects that smoking has on muscles.
In 2011 the researchers published the results of another animal experiment in which they had studied the effects of cigarette smoke. [J Toxicol Sci. 2011 Jun;36(3):261-6.] In that experiment they observed that exposure to tobacco smoke caused the immune cells in the intestines to use more glutamine. That might explain why the amount of BCAAs goes down as a result of exposure to cigarette smoke: smokers' bodies use larger amounts of BCAAs to synthesise glutamine.

Source:
J Toxicol Sci. 2014;39(2):331-7.

More:
Sweet-toothed smoker is less strong 30.01.2011
Stop smoking, grow faster 27.05.2010